The one you’ve seen on every longevity feed. Cellular energy currency.
NAD+ is a fundamental coenzyme involved in over 500 enzymatic reactions across cellular metabolism. Research indicates its role as a substrate for sirtuins (SIRT1–7), which regulate gene expression, mitochondrial function, and stress response pathways. It also serves as a substrate for PARP enzymes involved in DNA repair signaling. Preclinical and clinical data suggest that injectable delivery may support bioavailability compared to oral administration, where significant degradation can occur in the digestive tract. Intended for research purposes.


NAD+ is a coenzyme involved in over 500 enzymatic reactions across cellular metabolism. Research highlights its role as a substrate for sirtuins, which regulate mitochondrial function and stress response, and for PARP enzymes involved in DNA repair signaling. Injectable delivery is studied for better bioavailability than oral routes, where NAD+ degrades significantly in digestion.
Research Use Only. These products have not been evaluated or approved by the FDA for use as drugs, therapeutics, diagnostics, or dietary supplements, and are not intended for administration to humans or animals. No product description or mechanism-of-action information constitutes a health claim or therapeutic endorsement. Any clinical use is at the sole discretion of a licensed healthcare provider in compliance with applicable laws. Individual results may vary.